null

SMILES Nc1ccc(cc1Cl)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=CYGCWJCVIJAEOL-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11622   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  170nM ΔG°:  -9.23kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  290nM ΔG°:  -8.91kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11622(β-CA inhibitor, 1 | 2-N-(4-amino-3-chlorobenz...)copy SMILEScopy InChI
Affinity DataKi:  450nM ΔG°:  -8.65kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed