null
SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(cc1)[C@@H]1CC(=O)NS1(=O)=O)C(N)=O
InChI Key InChIKey=UILYPHAKDBTKQV-UFYCRDLUSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 13465
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte Corporation
Curated by ChEMBL
Incyte Corporation
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition constant against protein-tyrosine phosphatase 1B by PNPP enzyme assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Incyte Corporation
Incyte Corporation
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2GX48SDPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2GX48SDPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte Corporation
Curated by ChEMBL
Incyte Corporation
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibitory concentration against protein-tyrosine phosphatase 1B by PNPP enzyme assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte Corporation
Curated by ChEMBL
Incyte Corporation
Curated by ChEMBL
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of Homo sapiens (human) PTP1B expressed in Escherichia coli using PNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte Corporation
Curated by ChEMBL
Incyte Corporation
Curated by ChEMBL
Affinity DataIC50: 135nMAssay Description:Inhibitory concentration against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte Corporation
Curated by ChEMBL
Incyte Corporation
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Incyte Corporation
Incyte Corporation
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2JW8C4XPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2JW8C4XPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte Corporation
Curated by ChEMBL
Incyte Corporation
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against protein-tyrosine phosphataseMore data for this Ligand-Target Pair