null

SMILES OC(=O)COc1c(Br)c(sc1C(O)=O)-c1ccc(NC(=O)CC(O)=O)cc1

InChI Key InChIKey=UYGDTHQGIZMLJM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14267   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)copy SMILEScopy InChI
Affinity DataKi:  140nM ΔG°:  -9.34kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0CBDPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University of Miami

Curated by ChEMBL
LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023T5PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Miami

Curated by ChEMBL
LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Inhibition of PTPN1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023T5PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University of Miami

Curated by ChEMBL
LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)copy SMILEScopy InChI
Affinity DataKi:  180nM ΔG°:  -9.19kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0CBDPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University of Miami

Curated by ChEMBL
LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023T5PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
University of Miami

Curated by ChEMBL
LigandPNGBDBM14267(4-bromo-3-(carboxymethoxy)-5-[4-(2-formamidoacetic...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of PTPRFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023T5PubMed