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SMILES Cc1cc(Br)ccc1NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=QDOYRUBXBHREAH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14710   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)copy SMILEScopy InChI
Affinity DataKi:  20nM ΔG°:  -10.5kcal/mole IC50: 180nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43RB5PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Leeds

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)copy SMILEScopy InChI
Affinity DataKi:  5.09E+4nM IC50: 4.15E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43RB5PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [R265A](Plasmodium falciparum)
University of Texas Southwestern Medical Center

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0JH3PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0JH3PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [H185A](Plasmodium falciparum)
University of Texas Southwestern Medical Center

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0JH3PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University of Texas Southwestern Medical Center

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0JH3PubMed