null

SMILES C[NH+](C)[C@H]1CCC([C@H](C1)C#N)n1cc(C(N)=O)c(Nc2ccc(cc2)S(=O)(=O)C(F)(F)F)n1

InChI Key InChIKey=WQPOTWFXOOAHHW-KMMYHCRNSA-O

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 147677   

TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM147677(US8962608, 27-1)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J101W0US Patent
TargetTyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM147677(US8962608, 27-1)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J101W0US Patent