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SMILES Clc1ccc(cc1Cl)C12CCN(C1)Cc1cc(ccc21)-c1ccc2[nH]c(=O)oc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 160597   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM160597(US9045468, 11(+) | US9045468, 11(-))copy SMILES
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CV4US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM160597(US9045468, 11(+) | US9045468, 11(-))copy SMILES
Affinity DataIC50: 3.90nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CV4US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM160597(US9045468, 11(+) | US9045468, 11(-))copy SMILES
Affinity DataIC50: 92.4nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CV4US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM160597(US9045468, 11(+) | US9045468, 11(-))copy SMILES
Affinity DataIC50: 19.6nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CV4US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM160597(US9045468, 11(+) | US9045468, 11(-))copy SMILES
Affinity DataIC50: 369nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CV4US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM160597(US9045468, 11(+) | US9045468, 11(-))copy SMILES
Affinity DataIC50: 50nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CV4US Patent