null

SMILES CO\N=C(/C)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1

InChI Key InChIKey=PSORSGLVGFXCQD-KGENOOAVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 166437   

TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166437(US9073833, 5)copy SMILEScopy InChI
Affinity DataIC50: 170nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PQJUS Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166437(US9073833, 5)copy SMILEScopy InChI
Affinity DataIC50: 3.24E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PQJUS Patent
TargetCathepsin G(Homo sapiens (Human))
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM166437(US9073833, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin G using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide as substrate measured for 180 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8G5MPubMed
TargetMyeloblastin(Homo sapiens (Human))
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM166437(US9073833, 5)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of Pr3 (unknown origin) using t-butyloxycarbonyl-Ala-Ala-Nva-thiobenzyl ester as substrate measured for 180 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8G5MPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166437(US9073833, 5)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human neutrophil elastase measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8G5MPubMed