null

SMILES CC(C)(C)NS(=O)(=O)c1ccccc1-c1cnc(c(F)c1)-c1cnc(N)nc1

InChI Key InChIKey=PPXJXQJZJRXYKC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 169270   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM169270(US9079866, 675 | US9745328, Compound 675 | US98848...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R3QUS Patent
TargetFlap endonuclease 1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM169270(US9079866, 675 | US9745328, Compound 675 | US98848...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H13446US Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM169270(US9079866, 675 | US9745328, Compound 675 | US98848...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78H8PUS Patent