null

SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1cc(F)ccc1N

InChI Key InChIKey=RYYDWFXFHFUPRT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 178097   

TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)copy SMILEScopy InChI
Affinity DataIC50: 153nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64T2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)copy SMILEScopy InChI
Affinity DataIC50: 479nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64T2PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)copy SMILEScopy InChI
Affinity DataIC50: 106nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7DPJUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)copy SMILEScopy InChI
Affinity DataIC50: 153nMAssay Description:The following non-trypsin coupled in-vitro HDAC enzymatic endpoint assay was used to assay the compounds of the invention. Below is a standardized pr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7DPJUS Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)copy SMILEScopy InChI
Affinity DataIC50: 479nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7DPJUS Patent
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)copy SMILEScopy InChI
Affinity DataIC50: 106nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64T2PubMed