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SMILES COc1c(O)ccc2O\C(=C/c3sccc3C(O)C(F)(F)F)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key InChIKey=MJQKPIOTILTXNU-ODLFYWEKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 18628   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18628((18Z)-12-methoxy-3,5,5-trimethyl-18-{[3-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataKi:  1.40nM ΔG°:  -11.2kcal/mole IC50: 0.400nM EC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18628((18Z)-12-methoxy-3,5,5-trimethyl-18-{[3-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataKi:  670nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18628((18Z)-12-methoxy-3,5,5-trimethyl-18-{[3-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataKi:  1.78E+3nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18628((18Z)-12-methoxy-3,5,5-trimethyl-18-{[3-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed