null

SMILES CN1CCN(CC1)c1nc(N)nc(Cc2cccc3ccccc23)n1

InChI Key InChIKey=ZJCMJVPWMYOZEM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 189352   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl.

Curated by ChEMBL
LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN696CPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£ degli Studi di Palermo

Curated by ChEMBL
LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [3H]histamine from human H4R expressed in Sf9 cell membranes co-expressed with G protein Gai2 and Gb1gamma2 incubated for 60 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NRFPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£ degli Studi di Palermo

Curated by ChEMBL
LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nM ΔG°:  -6.66kcal/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6P93PubMed