null

SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1

InChI Key InChIKey=IKSFNOMXHPMYIQ-AWEZNQCLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 19134   

TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8GGNPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic tetrapeptide RHK(Ac)K(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8GGNPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN16FWPubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8GGNPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN16FWPubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8GGNPubMed