null
SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1
InChI Key InChIKey=IKSFNOMXHPMYIQ-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 19134
Affinity DataIC50: 29nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic tetrapeptide RHK(Ac)K(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite SpA
Curated by ChEMBL
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair