null

SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2o1)C(=O)N[C@@H]1CC[C@H](C)N(CC1=O)S(=O)(=O)c1ccccn1

InChI Key InChIKey=BWYBBMQLUKXECQ-TYPHKJRUSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19781   

TargetProcathepsin L(Homo sapiens (Human))
GSK

LigandPNGBDBM19781((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  3.90nM ΔG°:  -11.3kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8XP5PubMed
TargetCathepsin K(Homo sapiens (Human))
GSK

LigandPNGBDBM19781((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -11.3kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8XP5PubMed
TargetCathepsin S(Homo sapiens (Human))
GSK

LigandPNGBDBM19781((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8XP5PubMed
TargetCathepsin K(Rattus norvegicus)
GSK

LigandPNGBDBM19781((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  790nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8XP5PubMed