null

SMILES CCc1cc(Nc2cc(=O)n(CCCCN3CCN(CC3C)c3c(F)cc4c(c3F)n(cc(C(O)=O)c4=O)C3CC3)c(=O)[nH]2)ccc1C

InChI Key InChIKey=BSSRCWTVYSAQCP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 21688   

TargetDNA polymerase III PolC-type(Bacillus subtilis)
GLSynthesis Inc.

Curated by ChEMBL
LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3DR1PubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
GLSynthesis Inc.

Curated by ChEMBL
LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataKi:  19nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed
TargetDNA polymerase III subunit alpha(Escherichia coli)
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataKi: >4.82E+5nM ΔG°: >-4.60kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataKi: >4.82E+5nM ΔG°: >-4.60kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed
TargetDNA polymerase alpha subunit B(Bos taurus (bovine))
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataKi: >4.82E+5nM ΔG°: >-4.70kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed
TargetDNA polymerase subunit gamma-1(Homo sapiens (Human))
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataKi:  6.84E+5nM ΔG°:  -4.49kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed
TargetDNA topoisomerase 4 subunit A [V210L]/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.36E+4nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed
TargetDNA gyrase subunit A/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988599PubMed