null

SMILES CC(C(O)=O)c1ccc(s1)C(=O)c1ccccc1

InChI Key InChIKey=GUHPRPJDBZHYCJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 223313   

TargetCaspase-1(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223313(Tiaprofenic acid)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-3(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223313(Tiaprofenic acid)copy SMILEScopy InChI
Affinity DataIC50: 810nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
LigandPNGBDBM223313(Tiaprofenic acid)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human UCHL5 expressed in Escherichia coli BL21 (DE3) codon cells assessed as reduction in cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49VFDPubMed
TargetCaspase-5(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223313(Tiaprofenic acid)copy SMILEScopy InChI
Affinity DataIC50: 470nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-9(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223313(Tiaprofenic acid)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed
TargetCaspase-4(Homo sapiens (Human))
University of Colorado

LigandPNGBDBM223313(Tiaprofenic acid)copy SMILEScopy InChI
Affinity DataIC50: 380nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53JQXPubMed