null
SMILES COC(C)(c1nc2nc(nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)-c1noc(=O)[nH]1)c1c(F)cccc1F
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 227678
TargetE3 ubiquitin-protein ligase Mdm2 [17-125](Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Merck Sharp & Dohme Corp.
US Patent
Affinity DataIC50: 0.452nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair