null

SMILES NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=XZOWICPSVWHCTC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 23802   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataKi:  150nM ΔG°:  -9.30kcal/moleT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CXDPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataKi:  152nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ386TPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataKi:  156nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataKi:  245nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20866NNPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataKi:  246nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ386TPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataIC50: 396nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut de Biologie Structurale

LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataIC50: 241nMAssay Description:Inhibition of basal ATPase activity of Eg5 by coupled pyruvate kinase/lactate dehydrogenase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32C6PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-labeled RHKK(Ac) LM peptide as substrate incubated for 60 mins by electrophoretic mobility...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FSMPubMed