null
SMILES Nc1ncnc2n(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@H]1CCCc2[nH]ncc12
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 246396
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
Affinity DataIC50: 60nMAssay Description:Assay Method B: BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy...More data for this Ligand-Target Pair