null
SMILES Cn1ncc2[C@H](CCCc12)n1nc(-c2ccc(cc2)C(=O)Nc2cc(ccn2)C(F)(F)F)c2c(N)ncnc12
InChI Key InChIKey=SIMFVULLGBPDGX-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 246398
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.
US Patent
Affinity DataIC50: 2.70nMAssay Description:Assay Method B: BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy...More data for this Ligand-Target Pair