null

SMILES Cn1ncc2[C@H](CCCc12)n1nc(-c2ccc(cc2)C(=O)Nc2cc(ccn2)C(F)(F)F)c2c(N)ncnc12

InChI Key InChIKey=SIMFVULLGBPDGX-IBGZPJMESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246398   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.

US Patent
LigandPNGBDBM246398(US9446130, 9 | US9718828, Example, 553)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H9977TUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.

US Patent
LigandPNGBDBM246398(US9446130, 9 | US9718828, Example, 553)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Assay Method B: BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806H6US Patent