null

SMILES CCn1c(nc2c(ncc(OCCCN)c12)C#CCO)-c1nonc1N

InChI Key InChIKey=LWLOLQIXHMFYND-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25004   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM25004(3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5K3HPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM25004(3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5K3HPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM25004(3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5K3HPubMed