null
SMILES C[C@@H](NC(=O)c1ccc(s1)C(=O)C(F)(F)F)c1ccccc1
InChI Key InChIKey=DPKHRWMGXRDLLO-SECBINFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 25158
Affinity DataIC50: 320nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome
Curated by ChEMBL
IRBM-Merck Research Laboratories Rome
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome
Curated by ChEMBL
IRBM-Merck Research Laboratories Rome
Curated by ChEMBL
Affinity DataIC50: 360nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair