null

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(cc3N(Cc3ccc(nc3)C#N)C2=O)-c2cn(C)nc2C)c1F

InChI Key InChIKey=WNQUARCCIKLBAE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 261975   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM261975(5-((3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- ...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent