null

SMILES Oc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O

InChI Key InChIKey=YRRAGUMVDQQZIY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 26655   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 430nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8783KPubMed
TargetAurora kinase B(Homo sapiens (Human))
Konkuk University

LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61J08PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24W4SPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Tokyo Institute of Technology

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of His-tagged human brain tau 3R MBD aggregation after 16 hrs by thioflavin T fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4M4QPubMed
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
University of Toyama

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+4nMAssay Description:Displacement of ANS from DAPK1 catalytic domain (1 to 285) (unknown origin) after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21838BMPubMed
TargetSialidase(Clostridium perfringens)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of Clostridium perfringens neuraminidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66NNPubMed
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C33PubMed
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C33PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C33PubMed
TargetThiosulfate sulfurtransferase(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C33PubMed
TargetChaperonin GroEL(Escherichia coli)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C33PubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
University of Porto

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human liver FBP1 incubated for 5 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1QH2PubMed
TargetAromatase(Homo sapiens (Human))
King's College London

Curated by ChEMBL
LigandPNGBDBM26655(2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human aromatase by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4JN9PubMed