null

SMILES CS(=O)(=O)Nc1nnc2cc(COc3ccc(Cl)c(Cl)c3)c(cn12)C1CC1

InChI Key InChIKey=XLCJRUIKGPCZSQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 268516   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent
LigandPNGBDBM268516(N-(6-cyclopropyl-7-((3,4-dichlorophenoxy)methyl)-[...)copy SMILEScopy InChI
Affinity DataIC50: 7.54nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XRZUS Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent
LigandPNGBDBM268516(N-(6-cyclopropyl-7-((3,4-dichlorophenoxy)methyl)-[...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]GX-545 from recombinant human NaV1.7 expressed in HEK293 cell membranes coexpressing Nav beta1 subunit after 18 hrs by liquid sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K92PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent
LigandPNGBDBM268516(N-(6-cyclopropyl-7-((3,4-dichlorophenoxy)methyl)-[...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XRZUS Patent