null

SMILES COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(s3)C#N)c2cc1OC

InChI Key InChIKey=PYVMYBZZIWFCPE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27448   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
GSK

LigandBDBM27448(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(t...)copy SMILEScopy InChI

Affinity DataIC50: 251nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ311MPubMed

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GSK

LigandBDBM27448(5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(t...)copy SMILEScopy InChI

Affinity DataIC50: 700nMAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0JZXPubMed