null
SMILES Cn1c(nc(-c2ccc(cc2)C#N)c(-c2ccc(C(N)=O)c(F)c2)c1=O)N1CCC(N)CC1
InChI Key InChIKey=CDBVASSEPGRDOD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 283256
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 550nMAssay Description:To analyze LSD1 inhibitor efficacy in cells, a CD11b flow cytometry assay was performed. LSD1 inhibition induces CD11b expression in THP-1 (AML) cell...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD-1 activity is based on Tnne Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.
US Patent
CELGENE QUANTICEL RESEARCH, INC.
US Patent
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair