null

SMILES Cc1nc2c(-c3ccc(Cl)cc3)n(nc2c(=O)n1CC(F)(F)F)-c1ccccc1Cl

InChI Key InChIKey=IXMNBHPNQQLFMV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 29061   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi:  0.600nM ΔG°:  -12.8kcal/mole EC50:  1nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47MGDPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79PMPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79PMPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47MGDPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79PMPubMed