null

SMILES Oc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1

InChI Key InChIKey=BUGPWXMPCMTLIX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3014   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3014(3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70D0NPubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3014(3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70D0NPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3014(3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70D0NPubMed
TargetProtein kinase C alpha type(Bos taurus (bovine))
Novartis Pharmaceuticals

LigandPNGBDBM3014(3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70D0NPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3014(3-((3-Hydroxyphenyl)amino)-4-((3-chlorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70D0NPubMed