null

SMILES Oc1cc(O)c2c(c1)c(C=C)cn(-c1ccc(O)c(F)c1)c2=O

InChI Key InChIKey=UZCGSEMPWJYIKG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312139   

TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

US Patent
LigandPNGBDBM312139(2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinyl...)copy SMILEScopy InChI
Affinity DataKi:  3.96nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25FRUS Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
GTX, Inc.

US Patent
LigandPNGBDBM312139(2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinyl...)copy SMILEScopy InChI
Affinity DataKi:  3.96nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XV9US Patent
TargetEstrogen receptor(Homo sapiens (Human))
GTX, Inc.

US Patent
LigandPNGBDBM312139(2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinyl...)copy SMILEScopy InChI
Affinity DataKi:  205nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XV9US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

US Patent
LigandPNGBDBM312139(2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinyl...)copy SMILEScopy InChI
Affinity DataKi:  205nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25FRUS Patent