null

SMILES O=C1Nc2cc3[nH]nc(-c4ccncc4)c3cc2CN1Cc1ccccc1

InChI Key InChIKey=ODIUJYZERXVGEI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 318045   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology, Inc.

US Patent
LigandPNGBDBM318045(US10301317, Example 1 | US9624228, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22809PPUS Patent
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM318045(US10301317, Example 1 | US9624228, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2TF2PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology, Inc.

US Patent
LigandPNGBDBM318045(US10301317, Example 1 | US9624228, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2TF2PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology, Inc.

US Patent
LigandPNGBDBM318045(US10301317, Example 1 | US9624228, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM89M0US Patent