null
SMILES Clc1cccc(C[C@H](NC(=O)c2ccccc2)C(=O)NCC#N)c1
InChI Key InChIKey=NFHCBRWUVWGFHZ-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 31970
Affinity DataKi: 20nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 3.16E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human liver cathepsin B assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of cathepsin K assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Affinity DataIC50: 794nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Affinity DataIC50: 251nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair