null
SMILES OC1(NC(=O)c2ccccc2)C(=O)c2ccccc2C1=O
InChI Key InChIKey=FICSYWUBABJDHB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 34 hits for monomerid = 32085
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.95E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
TargetRNA-editing ligase 1, mitochondrial(Trypanosoma brucei brucei)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.37E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.82E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.81E+3nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in 25 mM DTT has been developed to assess actives that were identified in the Cdc25B HTS ...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.93E+3nMAssay Description:The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.99E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.31E+3nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in Catalase has been developed to assess actives that were identified in the Cdc25B HTS A...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in 25 mM DTT with Catalase has been developed to assess actives that were identified in t...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in Beta-Mercaptoethanol (BME) has been developed to assess actives that were identified i...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in Glutathione (GSH) has been developed to assess actives that were identified in the Cdc...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.87E+4nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.26E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-alpha catalytic subunit(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.90E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 828nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
Affinity DataEC50: 1.55E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
Affinity DataEC50: 1.64E+4nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 4.39E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetSentrin-specific protease 6(Homo sapiens (Human))
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 2.39E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 6.99E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 3.22E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
TargetCaspase-9(Homo sapiens (Human))
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 6.48E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.55E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 3.27E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.42E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair