null

SMILES Cn1ccnc1Sc1cc(C(=O)Nc2nccs2)c(N)cc1F

InChI Key InChIKey=YUCYMQBDBXVNCE-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34071   

TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Shanghai Institutes for Biological Sciences

LigandPNGBDBM34071(benzamide derivative, 6)copy SMILEScopy InChI
Affinity DataIC50: 4.39E+4nMpH: 7.2 T: 2°CAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6PK0PubMed
TargetHexokinase-4(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM34071(benzamide derivative, 6)copy SMILEScopy InChI
Affinity DataKd:  360nMAssay Description:Binding affinity to human pancreatic N-terminal His6-tagged glucokinase isoform 1 expressed in Escherichia coli BL21(DE3) by stopped-flow fluorometri...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM34071(benzamide derivative, 6)copy SMILEScopy InChI
Affinity DataEC50:  67.1nMAssay Description:The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...More data for this Ligand-Target Pair