null
SMILES CC(C)Oc1cc(CC[C@@H](C)N2Cc3ccc(F)cc3C2)ccc1O
InChI Key InChIKey=XSGCBOOLGAIFRX-OAHLLOKOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 349521
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.
US Patent
COGNITION THERAPEUTICS, INC.
US Patent
Affinity DataKi: 9.10nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.
US Patent
COGNITION THERAPEUTICS, INC.
US Patent
Affinity DataKi: 9.10nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.
US Patent
COGNITION THERAPEUTICS, INC.
US Patent
Affinity DataKi: 9.10nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
COGNITION THERAPEUTICS, INC.
US Patent
COGNITION THERAPEUTICS, INC.
US Patent
Affinity DataIC50: 480nMAssay Description:Representative sigma-2 antagonists test compounds do not induce neuronal or glial toxicity with acute or chronic dosing in vitro. The sigma-2 recepto...More data for this Ligand-Target Pair