null
SMILES O=c1[nH]cnc2n[nH]cc12
InChI Key InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 42 hits for monomerid = 35440
Affinity DataKi: 7.00E+3nMAssay Description:Inhibitory activity against Xanthine OxidaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as uric acid formation using xanthine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.43E+3nMpH: 7.8 T: 2°CAssay Description:The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMpH: 7.6 T: 2°CAssay Description:Bovine milk XO activity was assayed spectrophotometrically by measuring the uric acid formation at 293 nm using a UV-visible spectrophotometer at 25&...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition of xanthine oxidase (XO) by each isolated phenolics was measured by following the decrease in the uric acid formation at 293nm at 25°...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 3.16E+4nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 1.5 mL of 50 mM potassium phosphate buffer (pH 7.5), 1 mL test sample solutions (5, 10, 25, 50, and 100 µM) was d...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against Xanthine OxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) by spectrophotometryMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:In vitro inhibitory concentration against Xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.82E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as uric acid formation by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of superoxide generationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of uric acid generationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as formation of formazan at 16 ug/ml after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of cow milk xanthine oxidaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of bovine milk xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 753nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as decrease of uric acid formation preincubated for 5 mins by UV-visible spectrophotometric analy...More data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of Xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Xanthine oxidaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate assessed as decrease in uric acid formation preincubated for 5 minsMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate measured for 6 mins at 25 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of bovine milk XO assessed as decrease in uric acid formation after 5 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare Limited
Curated by ChEMBL
Piramal Healthcare Limited
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of bovine xanthine oxidase-mediated uric acid production after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis)
Pontif£cia Universidade Cat£lica do Rio Grande do Sul (PUCRS)
Curated by ChEMBL
Pontif£cia Universidade Cat£lica do Rio Grande do Sul (PUCRS)
Curated by ChEMBL
Affinity DataKd: 1.00E+6nMAssay Description:Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.19E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair