null

SMILES COc1ccc2nc(Cc3nc4n(C5CC5)c(=O)[nH]c(=O)c4n3Cc3ccccc3)[nH]c2c1

InChI Key InChIKey=FFSQYZANLRAXHZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357745   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357745(KM-05-125/(I-13) | US10214530, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357745(KM-05-125/(I-13) | US10214530, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357745(KM-05-125/(I-13) | US10214530, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 960nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357745(KM-05-125/(I-13) | US10214530, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent