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SMILES NCC(c1ccccc1)c1ccccc1

InChI Key InChIKey=RXMTUVIKZRXSSM-UHFFFAOYSA-N

PDB links: 10 PDB IDs contain this monomer as substructures. 10 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 35929   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataKi:  4.61E+3nMAssay Description:Binding affinity of the compound was performed using [3H]-ketanserin as the radioligand and stably transfected NIH3T3 cells expressing the 5-hydroxyt...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23T9GJ6PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataKi:  4.61E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZTRPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataKi:  4.61E+3nM ΔG°:  -7.23kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7FN6PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor expressed NIH3T3 cells using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1Q80PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7FN6PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataIC50: 5.82E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)copy SMILEScopy InChI
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V92PubMed