null
SMILES [O-]C(=O)CCCc1ccccc1
InChI Key InChIKey=OBKXEAXTFZPCHS-UHFFFAOYSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 36184
Affinity DataKi: 6.34E+3nMAssay Description:Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Technical University of Denmark
Curated by ChEMBL
Technical University of Denmark
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SIRT5More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Broad Institute of Harvard and MIT
Curated by ChEMBL
Broad Institute of Harvard and MIT
Curated by ChEMBL
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 36184
ITC DataΔG°: -3.60kcal/mole −TΔS°: -0.783kcal/mole ΔH°: -2.81kcal/mole logk: 435
pH: 6.9 T: 25.00°C
pH: 6.9 T: 25.00°C