null

SMILES FC(F)(F)COc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F

InChI Key InChIKey=WHMPVBWIYHEQGL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 373162   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
GSK

LigandPNGBDBM373162(2-(1-{[2-(2,2,2- trifluoroethoxy)phenyl]methyl}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8PBQUS Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
GSK

LigandPNGBDBM373162(2-(1-{[2-(2,2,2- trifluoroethoxy)phenyl]methyl}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD3 was determined in 384-well plate format under the following reaction conditions: 1 nM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8PBQUS Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
GSK

LigandPNGBDBM373162(2-(1-{[2-(2,2,2- trifluoroethoxy)phenyl]methyl}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8PBQUS Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
GSK

LigandPNGBDBM373162(2-(1-{[2-(2,2,2- trifluoroethoxy)phenyl]methyl}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8PBQUS Patent