null

SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCC(CC1)N1CCOCC1

InChI Key InChIKey=XZALXIFAYPBZQA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 391743   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84F65US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84F65US Patent
TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84F65US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84F65US Patent
TargetEpidermal growth factor receptor [1-745,751-1210](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84F65US Patent
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84F65US Patent