null

SMILES CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=CMRJIHMIAAPULE-LGEGPZQVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 391812   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
GSK

LigandPNGBDBM391812(US10300074, Compd 8 | US11111270, Compound 8)copy SMILEScopy InChI
Affinity DataKi:  3.75E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04VGUS Patent
TargetE3 ubiquitin-protein ligase XIAP [265-330](Homo sapiens (Human))TBA
LigandPNGBDBM391812(US10300074, Compd 8 | US11111270, Compound 8)copy SMILEScopy InChI
Affinity DataKi:  3.75E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185NQUS Patent
LigandPNGBDBM391812(US10300074, Compd 8 | US11111270, Compound 8)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185NQUS Patent
LigandPNGBDBM391812(US10300074, Compd 8 | US11111270, Compound 8)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04VGUS Patent