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SMILES CCOc1ccc2cc(ccc2n1)-c1nn(CC2CCN(C)CC2)c2ncnc(N)c12

InChI Key InChIKey=NANLXDNSBZTQHI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 416549   

TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
University of Washington

US Patent
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JT9US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

US Patent
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M048G9US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

US Patent
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant Toxoplasma gondii CDPK1 using Biotin-C6-PLARTLSVAGLPGKK as substrate after 90 mins in presence of ATP by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4P8BPubMed
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))TBA
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant FLAG-tagged PKD3 (unknown origin) expressed in HEK293T cells using Syntide-2 as substrate measured after 15 mins by ADP-Glo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JQGPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4P8BPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))TBA
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Inhibition of recombinant FLAG-tagged PKD1 (unknown origin) expressed in HEK293T cells using Syntide-2 as substrate measured after 15 mins by ADP-Glo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JQGPubMed
TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))TBA
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant FLAG-tagged PKD2 (unknown origin) expressed in HEK293T cells using Syntide-2 as substrate measured after 15 mins by ADP-Glo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JQGPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University of Washington

Curated by ChEMBL
LigandPNGBDBM416549(US10307425, Example 15 | US10632122, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chicken Src using AcEIYGEFKKK as substrate after 90 mins in presence of ATP by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4P8BPubMed