null

SMILES CN1CCc2ccc(OCCCN3CCN(CC3)c3ccccc3F)cc2C1=O

InChI Key InChIKey=JSYJUUGAOMCCSL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 423314   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  24.5nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  29.9nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  32.1nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  54.8nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent
TargetD(2) dopamine receptor(Rattus norvegicus (rat))TBA
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  117nMAssay Description:Displacement of [3H]spiperone from D2 receptor in rat striatum measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  262nMAssay Description:Displacement of [3H](+)8-OH-DPAT from rat cerebral cortex 5HT1A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  306nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K6MPubMed
TargetHistamine H1 receptor(RAT)
NHWA PHARMA. CORPORATION

US Patent
LigandPNGBDBM423314(US10501452, Compound 20)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Histamine H1: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FR6US Patent