null
SMILES CN(C)CC1(CCCCC1O)c1ccc2ccccc2c1
InChI Key InChIKey=XMTSFSJFANMZNO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 48 hits for monomerid = 433736
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 94nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 140nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 18nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 9.71E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.70E+3nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 97nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 538nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 464nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 36nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 250nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 229nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 289nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 330nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 680nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 43nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 413nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 260nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 139nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 309nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.90E+3nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 152nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 36nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 9.60nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 230nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 13nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 194nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 40nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 45nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.
US Patent
SUNOVION PHARAMCEUTICALS INC.
US Patent
Affinity DataIC50: 5.76E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair