null

SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1ccnc(c1)C1CC1

InChI Key InChIKey=NAXCUEOPBFVRKE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 443895   

TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM443895(2-(2-cyclopropylpyridin-4-yl)-3-isopropyl-5-(piper...)copy SMILEScopy InChI
Affinity DataIC50: 46.2nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97K0US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM443895(2-(2-cyclopropylpyridin-4-yl)-3-isopropyl-5-(piper...)copy SMILEScopy InChI
Affinity DataIC50: 76.6nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97K0US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM443895(2-(2-cyclopropylpyridin-4-yl)-3-isopropyl-5-(piper...)copy SMILEScopy InChI
Affinity DataIC50: 99nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM443895(2-(2-cyclopropylpyridin-4-yl)-3-isopropyl-5-(piper...)copy SMILEScopy InChI
Affinity DataIC50: 92nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM443895(2-(2-cyclopropylpyridin-4-yl)-3-isopropyl-5-(piper...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97K0US Patent