null
SMILES COc1cc(\C=C\C(=O)C(C(=O)CO)C(=O)\C=C\c2ccc(O)c(CO)c2)ccc1O
InChI Key InChIKey=BOSYBSXTFKWEEZ-KBXRYBNXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 445058
TargetNeutrophil collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
Affinity DataIC50: 3.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
Affinity DataIC50: 1.60E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
Affinity DataIC50: 4.80E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
Affinity DataIC50: 3.50E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
Affinity DataIC50: 1.60E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
US Patent
Affinity DataIC50: 4.80E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair