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SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=OROAFUQRIXKEMV-LDADJPATSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50011977   

TargetType-1 angiotensin II receptor A(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38R2NPubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38R2NPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRFDrugBank
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 363nMAssay Description:Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteriesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0JC7PubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20JNPubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 5.79E+4nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of [125I]-AII specific binding towards Angiotensin II receptor in rat mesenteric membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9WBVPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the presence of 0.25% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRFDrugBank
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 363nMAssay Description:Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteriesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0JC7PubMed