null

SMILES Cc1cn([C@@H]2O[C@H](CO)C=C2)c(=O)[nH]c1=O

InChI Key InChIKey=XNKLLVCARDGLGL-JGVFFNPUSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50013111   

TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Michigan Cancer Foundation

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  5.80E+5nMAssay Description:Inhibitory affect against rabbit thymus thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZQSPubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Michigan Cancer Foundation

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  6.15E+5nMAssay Description:Inhibitory affect against rabbit thymus thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZQSPubMed
TargetThymidine kinase, cytosolic(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+6nMAssay Description:Competitive inhibition against rat cytoplasmic Thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6ZBJPubMed
TargetThymidine kinase 2, mitochondrial (Predicted)(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  3.25E+6nMAssay Description:Competitive inhibition against rat mitochondrial thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6ZBJPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataEC50:  450nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639Q86PubMedDrugBank
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Effective concentration that reduces HIV-induced cytopathic effect by 50% was determined by reverse transcriptase (RT) assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7JBDPubMedDrugBank
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataEC50:  500nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutantMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639Q86PubMedDrugBank
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12S1PubMed
TargetAlbumin(Homo sapiens (Human))
Mercer University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to human serum albumin with excitation at 280 nm after 2 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82W0PubMed
TargetRecBCD enzyme subunit RecD(Escherichia coli str. K-12 substr. MG1655)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.29E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0JXGPCBioAssay
TargetReverse transcriptase(Human immunodeficiency virus 1)
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase-mediated thymidine incorporation into D23/D36 primer-template preincubated for 15 mins by polyacrylamide gel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0XQ1PubMed
TargetRecBCD enzyme subunit RecD(Escherichia coli str. K-12 substr. MG1655)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6.03E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0JXGPCBioAssay
TargetRecBCD enzyme subunit RecD(Escherichia coli str. K-12 substr. MG1655)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50013111(1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 7.25E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0JXGPCBioAssay