null

SMILES COc1cccc(Cn2cc(C(=O)Nc3ccc(C)c(c3)S(=O)(=O)N3CCOCC3)c(n2)-c2ccc(C)cc2)c1

InChI Key InChIKey=KQSPAAPFKIEUGH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015421   

TargetBile acid receptor(Homo sapiens (Human))
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015421(CHEMBL3264644)copy SMILEScopy InChI
Affinity DataIC50: 469nMAssay Description:Inhibition of GW4064-induced transactivation of FXR (unknown origin) expressed in HEK293T cells after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NMWPubMed
TargetBile acid receptor(Homo sapiens (Human))
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015421(CHEMBL3264644)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human GST-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8NMWPubMed