null

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1

InChI Key InChIKey=AJSUGOHRKILWCK-ZZTWKDBPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016033   

TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24VDZPubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24VDZPubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24VDZPubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7T14PubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7T14PubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7T14PubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50016033(CHEMBL3085574 | {1-[1-{1-[2-(1-Benzylcarbamoyl-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152M6PubMed